Louisville football is taking on the SMU Mustangs this weekend, and with the Cardinals fans hoping for another nine-win season, this road game is set to be a huge challenge for Jeff Brohm's Cardinals. SMU is one of the top teams in the ACC, as the Mustangs are 7-3 on the season, but 5-1 in the ACC.
The Mustangs and the Cardinals both defeated Miami this season, giving the Hurricanes their two losses. Now, in this crucial matchup as SMU tries to keep its ACC Championship dreams alive, and Louisville tries to play spoiler, the Cardinals are given a massive obstacle as the injury bug hit them hard this weekend.