Louisville set a school and ACC record for offensive yards in a single game, and Lamar Jackson was briefly the first player in FBS history to throw for 400 yards and rush for 200 more in a single game. Jackson lost that distinction with a negative 2-yard run on his final carry of the game, putting him at a 199 yards, but the Cards still routed Syracuse, 62-28.
Despite his wide receivers dropping no fewer than nine passes, Jackson still managed to add 411 passing yards to his total, finishing the game with a U of L record 610.