Week 6 is suddenly one of the most important games on Louisville’s schedule. In the wide-open ACC, Virginia has quickly become a top contender after knocking off Florida State in Charlottesville on Friday and cracking the AP Top 25 at No. 24. So, Jeff Brohm will need his team, and its biggest offensive playmaker, healthy to take down the Cavaliers at home.
Sophomore running back Isaac Brown has yet to miss a game this season and leads the Cardinals with 268 rushing yards on 33 carries, but has been limited for most of the year. Last week against Pitt, Brown carried the ball 14 times, but managed just 20 yards, while backup Duke Watson, after injuring his ankle, shouldered much of the load in the backfield to close out the victory.