The Louisville football program has their biggest test of the 2025 season so far, and they might be doing it with a thin locker room. Cardinals fans learned on Saturday that Louisville is without some key players, and their star running backs are still questionable.
Louisville fans have circled this game as a priority, as road games at Pitt have historically caused trouble for the Cardinals, with a 0-3 record on the road against Pitt since joining the ACC. All Louisville fans remember the heartbreaking loss in 2023 when the Cardinals were at the highest of highs, coming off a dominant win over No.