Louisville football must take care of business in these three key areas to beat Eastern Kentucky.
The Louisville Cardinals' 2025 season is kicking off in just five days against the Eastern Kentucky Colonels, and Jeff Brohm opens up as a dominant 38.5-point favorite. While the Cardinals appear to be a lock, many fans know that anything can happen in college football.
So, while many think Louisville will win and cover, here are three reasons Louisville football could run into problems with Eastern Kentucky.