Denver Broncos running back Javonte Williams suffered significant knee damage on Sunday and is done for the season, multiple outlets reported Monday.
NFL Network reported Williams has multiple ligament tears, including the ACL and lateral collateral ligament.
Williams initially was helped off the field after the first play of the third quarter but soon was carted from the Denver sideline to the locker room.
Broncos coach Nathaniel Hackett said after the 32-23 loss to the Las Vegas Raiders that Williams and edge rusher Randy Gregory (knee) would undergo MRIs.
Williams is Denver's leading rusher with 204 yards on 47 carries.