travel to Glendale, Arizona on Sunday to take on division rivals, the Arizona Cardinals (+3.5). Both teams are 1-1, losing the season openers and then squaring their records with wins in Week 2. The Rams have won 10 of the previous meetings dating back to 2017 and en route to the Super Bowl title, beat Arizona 34-11 in last years opening playoff game.
After signing a new $230.5 million contract, Cardinal quarterback Kyler Murray has been hot and cold. He was stymied in a 44-21 Week 1 loss to the Kansas City Chiefs (-5.