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Rams 2022 schedule: Buffalo Bills is ‘likely’ season opener, according to report

The Los Angeles Rams will face off against the Buffalo Bills in the season opener, according to a report from Matt Warren at Buffalo Rumblings. With the news on Tuesday morning that the Rams would face the Denver Broncos on Christmas Day, the Bills emerged as the most likely opponent for the all important season opener, per Warren’s schedule source.

Since we know that the reigning Super Bowl champion almost always hosts the NFL season opener, and not against a boring opponent, and rarely against a division foe, there were only so many options left on the table.