Two assistant coaches were fired and Sam Darnold was activated from injured reserve and returned to practice -- and a crowded but unclear quarterback depth chart -- on Monday.
The Panthers (2-7) made the moves following a 42-21 defeat Sunday in which Baker Mayfield entered in relief of PJ Walker, who was pulled in a dismal showing against the Bengals (5-4).
The Panthers fired cornerbacks coach Evan Cooper and defensive line coach Paul Pasqualoni on Monday.
Carolina was scorched for a season-worst 464 yards and 241 rushing yards against Cincinnati and has three days to get ready for Thursday's visit from the Atlanta Falcons (4-5).