Colts rule out RB Jonathan Taylor (ankle) vs. Broncos

Sep 18, 2022; Jacksonville, Florida, USA; Indianapolis Colts running back Jonathan Taylor (28) runs off the field after the Indianapolis Colts are defeated by the Jacksonville Jaguars at TIAA Bank Field. Mandatory Credit: Douglas DeFelice-USA TODAY SportsIndianapolis Colts running back Jonathan Taylor will miss Thursday night's game at Denver with an ankle injury.

The Colts (1-2-1) also ruled out linebacker Shaquille Leonard, safety Julian Blackmon and defensive end Tyquan Lewis for the Week 5 game against the Broncos (2-2).

On Tuesday, Colts head coach Frank Reich and Taylor both said they were hopeful that the injury wasn't severe enough to keep him out. "But if you can't go, you can't go,"…