The accompanying chart presents the Rams' current 53-man roster, depth chart and just-announced Practice Squad signings:
| C | Tim Barnes | Demetrius Rhaney | |
| RG | Rodger Saffold | Garrett Reynolds | |
| LG | Jamon Brown | Cody Wichmann | |
| RT | Rob Havenstein | Andrew Donnal | |
| LT | Greg Robinson | Darrell Williams | |
| TE | Lance Kendricks | Cory Harkey | |
| TE | Jared Cook | ||
| WR | Brian Quick | Tavon Austin | Bradley Marquez |
| WR | Kenny Britt | Stedman Bailey | Chris Givens |
| RB | Tre Mason | Benny Cunningham | Chase Reynolds |
| RB | Todd Gurley | Isaiah Pead | |
| QB | Nick Foles | Case Keenum | Sean Mannion |
| PK | Greg Zuerlein | ||
| P | John Hekker | ||
| LS | Jake McQuaide | ||
| DT | Aaron Donald | Nick Fairley | |
| DT | Michael Brockers | Ethan Westbrooks | |
| DE | Chris Long | William Hayes | |
| DE | Robert Quinn | Eugene Sims | |
| MLB | James Laurinaitis | Bryce Hager | |
| OLB | Alec Ogletree | Daren Bates | |
| OLB | Akeem Ayers | Cameron Lynch | |
| CB | Janoris Jenkins | Marcus Roberson | |
| CB | Trumaine Johnson | Lamarcus Joyner | |
| SS | T. |