The Lakers (3-17) will play their fifth straight game on the road on Monday, visiting the Toronto Raptors (12-9).
After falling to the Detroit Pistons on Sunday, the Lakers will have to muster up enough energy to defeat the Raptors while playing on the second night of a back-to-back.
Toronto visited Staples Center on Nov. 20, pulling away in the second half for 102-91 victory.
Center Jonas Valanciunas suffered a hand injury against the Lakers, and is expected to be out an additional few weeks.
The Lakers are healthy, although a stomach ailment limited Kobe Bryant on Sunday against the Pistons.