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Source: Derwin James out as ailing Chargers face Dolphins

LOS ANGELES -- The Los Angeles Chargers will be without several key players on defense when they face the Miami Dolphins on Sunday Night Football.

Safety Derwin James Jr., defensive lineman Sebastian Joseph-Day and cornerback Bryce Callahan will be out because of injuries, a source told ESPN.

Right tackle Trey Pipkins III, listed as doubtful, also is expected to be out as he continues to nurse a knee injury that sidelined him last Sunday.

The Chargers are 6-6, and still looking for their first victory against a team with a winning record (0-4), as they prepare for the Dolphins (8-4).