The San Diego Chargers and Cincinnati Bengals each earned season-opening wins on the West Coast in Week 1 and will meet for the first time since the former upset the latter in the 2014 playoffs as 6.5-point road underdogs. The Chargers won that postseason matchup 27-10 to snap a three-game losing streak against the Bengals both straight-up and against the spread.
Point spread: Bengals opened as three-point favorites; the total was 45.5 early in the week, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
NFL pick, via Odds Shark computer: 26.