The Chargers got Joey Bosa back Sunday and had a 12-point lead in the second half.
Yet they failed to put away Denver in 23-22 loss at StubHub Center, the defeated ending their six-game winning streak.
Broncos kicker Brandon McManus made a 34-yard field goal as time expired. The points were set up by a Case Keenum-To-Courtland Sutton 30-yard pass.
The Chargers had opened a 19-7 lead on their first drive of the second half, going 75 yards in nine plays. Philip Rivers passed six yards to Antonio Gates for the touchdown.