Bortles looked like he revived the Jags offense after three straight dull performances behind Chad Henne. He threw for 149 yards and a touchdown, completing 15/17 passes.
Toby Gerhart scored his first rushing touchdown as a Jaguar, punching one in from a yard out. He had 20 rushing yards on five carries.
Allen Hurns leads the Jaguars with 62 receiving yards on three catches.
Phillip Rivers found Eddie Royal for a 47 yard touchdown early in the second quarter, and then again from 43 yards, adding to his 206 yard first half.
Donald Brown got the start for a backfield that is without Ryan Matthews and Danny Woodhead, rushing for nine yards on four carries.
Royal had two touchdown receptions for 100 yards on four catches.
Stat To Keep An Eye On: Gerhart's rushing touchdown in the second quarter was the Jaguars' first rushing touchdown since November of 2013.
Jacksonville: Blake Bortles - 15/17, 143 yards and one touchdown
San Diego: Phillip Rivers: 16/18, 206 yards and two touchdowns
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