The Padres (21-25) have dropped five of their last six games, while the Angels (23-22) were coming off splitting a 10-game road trip on the East Coast.
With the score tied at 3 and Kevin Quackenbush on the mound in the bottom of the ninth, Marc Krauss drew a one-out walk and Johnny Giavotella followed with a single up the middle, putting runners on the corners. Kimbrel entered the game, struck out Erick Aybar and intentionally walked Mike Trout to load the bases. Shortly after that, Pujols came through with his eighth career walk-off hit or RBI.