Mohamed Salah hit four goals as Egypt cruised to victory in their first qualifier for the 2026 Fifa World Cup but Nigeria were held to a 1-1 draw at home by minnows Lesotho.
Motlomelo Mkwanazi gave Lesotho, ranked 153rd in the world - 113 places below Nigeria, a shock lead with a 56th-minute goal from a corner.
West Brom centre-back Semi Ajayi powerfully headed in Kelechi Iheanacho's corner to level 11 minutes later but the Super Eagles could not find a winner in their Group C opener in a rainy Uyo.
Jose Peseiro's side had dominated the first half but paid for their profligacy as Iheanacho saw a free-kick saved, Nottingham Forest striker Taiwo Awoniyi failed to capitalise on a promising cut-back and Ademola Lookman had a low shot across goal saved.