History will be made as the Reds meet their local rivals in L4 on Sunday November 17, with kick-off scheduled for 3pm GMT.
Tickets are on sale now and the match forms part of the FA Women’s Football Weekend during the next men’s international break.
Read on below as Liverpoolfc.com spoke to Becky Jane, Melissa Lawley and boss Vicky Jepson to preview the occasion...
An historic moment for women’s football on Merseyside ud83dude4c Next month, we'll play our first ever league game at Anfie… https://t.co/t9YgL2uehg
— LiverpoolFCW (Liverpool FC Women) 24th Oct 08:30
Vicky Jepson.