The duo are named in Jürgen Klopp’s first competitive starting XI of the season, with fellow new arrivals Fabinho and Xherdan Shaqiri on the bench.
Elsewhere, Joe Gomez partners Virgil van Dijk in defence, while Jordan Henderson is also among the substitutes.
Liverpool: Alisson, Alexander-Arnold, Gomez, Van Dijk, Robertson, Milner, Wijnaldum, Keita, Mane, Salah, Firmino.
Subs: Karius, Clyne, Fabinho, Henderson, Sturridge, Lallana, Shaqiri.