Arsenal midfielder Thomas Partey has suffered a setback in his bid to return from a thigh injury.
Takehiro Tomiyasu remains on international duty with Japan, but Gabriel Jesus is fit after a minor knee issue.
Liverpool's Darwin Nunez faces a fitness test on the foot injury he suffered against Chelsea.
Alexis Mac Allister is expected to be available despite suffering a blow to his knee towards the end of that game.
Wataru Endo is unavailable due to international duty and Stefan Bajcetic, Mohamed Salah and Kostas Tsimikas remain out.
MATCH FACTS
Head-to-head
- This will be the fifth fixture in English league history to be played 200 times.