The 28-year-old midfielder, who joined the club from Sunderland in June 2011, will play his 300th match for the Reds if selected at Molineux.
The skipper is the only surviving player from either Liverpool or Wolves who featured the last time the clubs met in the league - a 3-0 away win for the Reds in January 2012.
For more need-to-know pre-match facts and figures, courtesy of club statistician Ged Rea, read on...
Liverpool's last eight Premier League meetings with Wolves have produced a total of 15 goals.
The Reds require four goals to record 150 in league games against the Midlands club, with this being the 95th league meeting.