The Reds go into this weekend’s round of Premier League fixtures in second place, five points ahead of sixth-placed United and five behind leaders Chelsea.
Mignolet was part of the last Liverpool team to win at the home of their fierce rivals, when two Steven Gerrard penalties and a late Luis Suarez goal earned the visitors a 3-0 victory in March 2014.
Of course, the Belgium international also played as Jürgen Klopp’s side claimed a 1-1 draw at Old Trafford in the second leg of last season’s Europa League last-16 tie, which followed a 2-0 win in the first leg.