Liverpool will be without injured captain Jordan Henderson for their opening Champions League Group A trip to Napoli on Wednesday.
However, fellow midfielder Thiago Alcantara is set to make his first appearance for a month.
Winger Hirving Lozano and forward Victor Osimhen could be available for Napoli after returning to training.
Injuries have left Liverpool particularly light in midfield, which led to their deadline-day loan move for Arthur Melo from Juventus.
The 26-year-old has not played a competitive match since his substitute appearance in May's Coppa Italia final and could make his Reds debut in Naples at the imposing Stadio Diego Armando Maradona.