Manchester United await news on whether Casemiro, Jonny Evans and Raphael Varane will be fit after they were forced off against Chelsea.
Victor Lindelof, Lisandro Martinez and Luke Shaw remain on the sidelines.
Liverpool expect to welcome back Wataru Endo after he sat out the win over Sheffield United due to a knock he sustained against Brighton.
Trent Alexander-Arnold, Alisson and Diogo Jota are not yet ready to return from injury.
MATCH FACTS
Head-to-head
- Manchester United have won just one of their last 11 league games against Liverpool (D4, L6), although it was in this exact fixture last season.