Liverpool full-back Andrew Robertson remains sidelined with the knee injury he suffered three weeks ago.
Curtis Jones may also be available but this game will come too soon for Alex Oxlade-Chamberlain and Naby Keita.
Brighton midfielder Enock Mwepu was hospitalised with illness while on international duty with Zambia and is unlikely to feature after returning to England for tests.
Tariq Lamptey is another doubt after reports of an unspecified training injury while with Ghana.
CHRIS SUTTON'S PREDICTION
Brighton had a good record at Anfield under Graham Potter, with a draw and win in their past two visits, but this is our first look at them under new boss Roberto De Zerbi.