Keita sustained a hamstring strain while on international duty with Guinea and is set to sit out the clash at the John Smith’s Stadium.
The Reds will check on Virgil van Dijk, Mohamed Salah, Sadio Mane and James Milner ahead of the contest, however.
Asked if he had a fitness update, Klopp told his pre-match press conference: “Not really. We had a session yesterday and a few of the boys trained, so we’ll have to see how they’ve reacted after that.
“The only thing that is pretty sure is that Naby will not be available; with all the rest we have to see how it develops.