Rhian Brewster, Harvey Elliott and Caoimhin Kelleher make their first senior appearances for the Reds in the third-round clash at Stadium MK.
Asked about their pre-match feelings and his thinking behind the line-up, Klopp told Sky Sports: “Not at all nervous. [They are] really excited and really looking forward to it.
“The boys did brilliant. We had to decide things like this long ago. Of course, Divock Origi would have been involved, Xherdan Shaqiri would have been involved, Nathaniel Clyne would have been involved.
“But when you don’t have these guys available, it was always clear and always the plan to do it with the young boys.