Rhian Brewster struck twice at Prenton Park and was followed on the scoresheet by Curtis Jones and Bobby Duncan, with senior squad members Nathaniel Clyne and Divock Origi the others to net.
The manager praised all of the youngsters involved on the night for their application and, with several first-team stars still unavailable in pre-season, acknowledged the need for them to grasp the chances they are given.
“They were all good,” Klopp, whose side next face Bradford City on Sunday, told Liverpoolfc.