The captain will feature for the 286th time for the club in the top flight should he be selected at West Ham United.
That would move Henderson beyond Reina and behind only Jamie Carragher (508 games), Steven Gerrard (504) and Sami Hyypia (318) for the Reds in the division.
For more pre-match facts and figures from LFC statistician Ged Rea, read on…
Liverpool have won 30 of the 49 meetings between the clubs in the Premier League, and have lost just nine of the last 64 clashes in the top flight.