Inter Miami's playoff hopes took a crushing blow following a dominant second-half performance from the Chicago Fire Wednesday.
Braces from former Liverpool player Xherdan Shaquiri and Maren Haile-Selassie sealed a 4-1 win for the hosts over the Herons, who once again found themselves without star, Lionel Messi.
Tata Martino's side emerges from the defeat still mathematically alive in the Easter Conference playoff chase but must win its remaining games as well as rely on help elsewhere if it is to cling on to the hope of making the postseason.