Fabinho has pulled out of Brazil's next's national team squad which almost certainly rules him out of Liverpool's Premier League clash with Manchester City next weekend.
The 27-year-old injured his thigh during the Reds' Champions League win over FC Midtjylland on Tuesday and was replaced by defender Rhys Williams in the first-half at Anfield.
The injury is a blow to Jurgen Klopp's side - who already have Virgil van Dijk out for most of this season with an ankle ligament problem - and Brazil have called up Everton midfielder Allan for their November fixtures in place of Fabinho.