Keita will sit out the Merseyside derby at Goodison Park due to a fitness issue, Jürgen Klopp detailed on Friday.
However, Mane and Thiago will return having resumed training at Melwood after testing positive for COVID-19 prior to the international break.
Elsewhere, Joel Matip is also in contention after returning to fitness and Jordan Henderson picked up his first minutes of football while on England duty since sustaining a knock for the Reds at Chelsea on September 20.