Brighton defender Tariq Lamptey will be unavailable due to suspension.
Former Liverpool midfielder Adam Lallana will have a thigh injury assessed but Leandro Trossard and Solly March should be fit.
Mohamed Salah is likely to start for Liverpool, having returned from a period of self-isolation to face Atalanta in midweek.
Jordan Henderson and Thiago Alcantara were both absent on Wednesday but could be involved against Brighton.
MATCH FACTS
Head-to-head
- Liverpool are on a run of nine consecutive victories against Brighton in all competitions, scoring 27 goals in the process.