Liverpool are without their No 1 goalkeeper again - just four days after his long-awaited return to the team.
Alisson is missing from the Reds starting XI with Giorgi Mamardashvili deputising for the Brazilian again.
It is understood it is down to illness rather than injury, which will come as a relief to fans of the Premier League champions who have lost eight of their last 11 with Alisson missing nearly two months of action.
Liverpool take on PSV Eindhoven at a bitterly cold Anfield this evening.
Arne Slot has been forced into the change – but it is not thought to be a recurrence of a hamstring injury that has plagued his campaign.