Next up for measurements on day two of the 2016 NFL Scouting Combine was the running backs. Here are their official measurements:
| Player | School | Height | Weight | Hand |
| Peyton Barber | Auburn | 5-10 | 228 | 9 3/8 |
| Devontae Booker | Utah | 5-11 | 219 | 8 5/8 |
| Tra Carson | Texas A&M | 5-11 | 227 | 9 1/4 |
| Alex Collins | Arkansas | 5-10 | 217 | 9 1/4 |
| Marshaun Coprich | Illinois State | 5-8 | 207 | 9 |
| Kenneth Dixon | Louisiana Tech | 5-10 | 215 | 9 1/2 |
| Kenyan Drake | Alabama | 6-1 | 210 | 9 3/4 |
| Ezekiel Elliott | Ohio State | 6-0 | 225 | 10 1/4 |
| Tyler Ervin | San Jose State | 5-10 | 192 | 9 1/8 |
| Josh Ferguson | Illinois | 5-9 | 198 | 9 |
| Glenn Gronkowski | Kansas State | 6-2 | 239 | 9 1/2 |
| Derrick Henry | Alabama | 6-3 | 247 | 8 3/4 |
| Quayvon Hicks | Georgia | 6-1 | 259 | 9 5/8 |
| Jordan Howard | Indiana | 6-0 | 230 | 9 |
| Andy Janovich | Nebraska | 6-1 | 238 | 9 3/4 |
| Devon Johnson | Marshall | 6-0 | 238 | 9 1/4 |
| Daniel Lasco | California | 6-0 | 209 | 9 1/8 |
| Tre Madden | USC | 6-0 | 223 | 9 3/8 |
| Keith Marshall | Georgia | 5-11 | 219 | 9 3/8 |
| Paul Perkins | UCLA | 5-10 | 208 | 9 |
| C J Prosise | Notre Dame | 6-0 | 220 | 8 1/2 |
| Wendell Smallwood | West Virginia | 5-10 | 208 | 9 1/4 |
| Kelvin Taylor | Florida | 5-10 | 207 | 8 1/4 |
| Shad Thornton | N. |