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Kentucky vs. Louisville basketball final odds and prediction

Related Topics: Kentucky, Louisville

When Kentucky and Louisville tip off tonight at the KFC Yum! Center, the rivalry finally returns to a fully charged state. For the first time in several seasons, both programs enter this matchup with genuine direction, national attention, and the kind of roster talent capable of swinging March conversations in November.

Louisville enters as a 4.5-point favorite, per FanDuel, and that reflects the early-season explosiveness of Pat Kelsey’s offense. The Cards are averaging 57 first-half points, a blistering pace built on tempo, spacing, and relentless rim pressure. Kentucky, on the other hand, brings the sort of defensive structure and connectivity that Kelsey’s group hasn’t seen yet.