The Royals were well represented at the 2016 All-Star Game in San Diego, sending: Salvador Perez, MVP Eric Hosmer, Wade Davis and Kelvin Herrera.
2016 marked the fourth consecutive season in which Kansas City has been represented by multiple All Star players:
- 2016: Perez, Hosmer, Davis, Herrera
- 2015: Lorenzo Cain, Alcides Escobar, Alex Gordon, Mike Moustakas, Perez, Davis, Herrera
- 2014: Perez, Gordon, Greg Holland
- 2013: Perez, Gordon, Holland
This marks the first time the Royals have had multiple All Star players in four consecutive seasons since 1986–89.