The Kansas City Chiefs open the 2025 NFL regular season against the Los Angeles Chargers on Sept. 5 in São Paulo at Arena Corinthians (8 p.m. ET, YouTube).
Coach Andy Reid and the rest of his staff will have to make a few tough decisions at the back end of their roster, especially at receiver, running back and cornerback. Unlike some previous years, the Chiefs' initial roster could feature more offensive linemen and defensive linemen, a circumstance that is in part because of season-ending injuries to edge rusher Felix Anudike-Uzomah and Janarius Robinson.