The beauty of daily fantasy football is that, unlike a season-long draft where someone is tied to their top players all year, any top players in the NFL can make their way into your lineup. While that can be a blessing, it can also be a curse.
While being able to roster Christian McCaffrey, Dalvin Cook, and Derrick Henry all at once if a player truly wants to, it is unlikely that all three running backs are all optimal play at their respective salaries for a particular week. There are many elements to decide which players will, and a large aspect of daily fantasy is the matchup a player has.