After a gritty 17-10 win over the Houston Texans, the Jacksonville Jaguars will look to end a five-game losing skid when they face the San Francisco 49ers in Week 4.
The last time the Jags beat San Francisco was in the distant year of 2005, 20 years ago. They're currently a 3.5-point underdog for the game. However, their odds might have increased a bit in light of the latest Nick Bosa news.
The Jaguars may not face Nick Bosa when they play the 49ers in Week 4
Nick Bosa suffered a knee injury in the 49ers' win over the Arizona Cardinals in Week 3.