The San Francisco 49ers placed tight end George Kittle on Injured Reserve after the season opener. That means that the Jacksonville Jaguars won't have to face the two-time First-Team All-Pro nod in Week 4. However, that may not be the only twist for the game.
Aside from Kittle, 49ers quarterback Brock Purdy is dealing with shoulder and toe injuries. His status against the New Orleans Saints in Week 2 is in question, and the fact that San Francisco 49ers head coach Kyle Shanahan says his team is in the market for a quarterback might be a sign that the former Iowa State product could miss extended time, including the Jaguars game.