In Week 4, the Jacksonville Jaguars will face what will arguably be their toughest challenge up until this point of the season: They'll fly to the West Coast to take on the San Francisco 49ers.
Currently, the Jags are a three-point underdog and will need to fix several issues (drops, inconsistent passing game) if they want to have a shot at pulling the upset. On the other hand, they have a few things going in their favor.
For instance, Jacksonville will be mostly healthy for the game. Only Dyami Brown was listed as questionable in the final injury report, and even then, there's a chance the fifth-year wideout will suit up.