Having come from behind late on to snatch three points against Watford on Wednesday, Tottenham have the genuine chance to push themselves into the top two of the Premier League.
Manchester City's shock loss on Tuesday means the gap is two points between second and third, giving Mauricio Pochettino the chance to overhaul the champions, if only briefly.
They will, however, have to overcome the very side who dealt defeat to the Citizens - Newcastle, led by Rafa Benitez.
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Though in the midst of an injury crisis, the Magpies have eased relegation worries with two recent wins and will be keen to draw themselves further away from the bottom of the table.