The defender replaces Calum Chambers for the Gunners but Mesit Ozil and Olivier Giroud are only substitutes as they recover after Euro 2016.
Arsenal has welcomed Laurent Koscielny back into their starting XI for their visit to Leicester City while Granit Xhaka starts for the Gunners for the first time.
Mesut Ozil and Olivier Giroud, meanwhile, are only substititutes as they continue to work their way back to fitness after Euro 2016.
Elswhere, Rob Holding is prefered at center back to Calum Chambers while Alex Oxlade-Chamberlain starts after scoring against Liverpool last week.
Premier League champion Leicester makes four changes from its defeat to Hull City on the opening day, with Nampalys Mendy making his first Premier League start since arriving from Nice in the summer.