Mamelodi Sundowns will be the home team in a Nedbank Cup semi-final match against Bidvest Wits in Soweto.
The Brazilians are chasing a domestic treble this season having already bagged the Telkom Knockout Cup title in December 2019.
Securing a place in the final would mean Pitso Mosimane is on track to achieve the record that is still held by Orlando Pirates - winning three domestic trophies in a single campaign.
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But they will have to work hard to achieve that as Wits, who have been sold to Tshakhuma Tsha Madzivhandila owner Masala Mulaudzi, will want to bow out in style as they will not exist beyond the current season.