With the NFL set to be unveil the 2025 regular season schedule for all 32 teams Wednesday, the Stampede Blue community is eager to discover who will be the first opponent to take on the Indianapolis Colts.
All 14 opponents the Colts will have to play in the 2025 regular season have been revealed as the AFC South is set to face the AFC West and NFC West in 2025. The Colts will hold five non-divisional games inside Lucas Oil Stadium and host the Broncos, Cardinals, Dolphins, Falcons, 49ers, Raiders, along with three divisional matchups against the Jaguars, Texans and Titans.