The Indianapolis Colts will travel to the Houston Texans (1 PM EST) to kick off the 2022 NFL season, but there are also a number of other games to make predictions on.
Among the tougher matchups to predict:
-Cleveland Browns at the Carolina Panthers (1 PM EST)
Baker Mayfield’s revenge game? This one should be interesting between two teams with new starting quarterbacks entering 2022. Mayfield will flip jerseys in this matchup, while Jacoby Brissett is the Browns starter until Deshaun Watson returns from his 11-game suspension.
-New England Patriots at the Miami Dolphins (1 PM EST)
These two divisional rivals always seem to play one another close, and the Patriots always seem to have their hands full in Miami.