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Rivers starts strong, but his late pick-six proves costly to Colts' playoff hopes in 48-27 loss

AP

Indianapolis Colts quarterback Philip Rivers (17) passes against the San Francisco 49ers during the first half Monday night in Indianapolis.

49ers Colts Football
Indianapolis Colts quarterback Philip Rivers (17) passes against the San Francisco 49ers during the first half of an NFL football game, Monday, Dec. 22, 2025, in Indianapolis.

49ers Colts Football
San Francisco 49ers head coach Kyle Shanahan, middle left, hugs Indianapolis Colts quarterback Philip Rivers after an NFL football game, Monday, Dec. 22, 2025, in Indianapolis.