The Colts play a really hard game tonight against one of the best teams in the entire league. They will be doing so with a defense who has been struggling most of the season. They actually have several players who are inactive on the defensive side of the ball as well.
For this game, Malik Hooker, Tyquan Lewis, Clayton Geathers, Darius Leonard, Rolan Milligan are all inactive for this game. Three of them are starters, while Lewis has started before as well. The Colts will be down a bunch of key guys on defense, but not on offense.